Endnote x7 word 2016 repeated citations short title

We also reviewed methods used to evaluate cognitive function in meningioma patients, and make recommendations for future studies. The objective of this systematic review was to evaluate the available data and the quality of studies on cognitive impairment in meningioma patients prior to and/or following treatment, and to document potential changes in cognitive dysfunction due to treatment (i.e., surgery with or without adjuvant radiotherapy). These tumors often grow to a considerable size before clinical symptoms appear because of the plastic potential of the brain. However, even meningiomas can cause cognitive deficits by putting pressure on brain tissue. Rapidly growing tumor types such as high-grade gliomas typically lead to more cognitive impairment than slowly growing tumors such as meningiomas. Less is known about cognitive functioning in meningioma patients and the impact of surgery and/or (adjuvant) radiotherapy. To date, most studies on cognitive functioning in brain tumor patients have focused on glioma patients. Cognitive functioning has a significant impact on HRQoL, and could even be a predictor of HRQoL. The assessment of health related quality of life (HRQoL) and cognitive function has become increasingly recognized as an important outcome measure in brain tumor research. Instead of considering survival as the sole endpoint, quality of survival is also considered. This prompts a different approach towards health care. Adequate diagnosis and treatment of cognitive deficits may ultimately lead to improved outcome and quality of life in meningioma patients.ДЄs a result of increasingly effective disease management, patients with brain tumors have better survival rates. Suggestions are given for future research. However, they still have impairments in a wide range of cognitive functions compared to healthy controls. Following surgery, most of these patients seem to improve in cognitive functioning. Study results suggest that most of meningioma patients are faced with cognitive deficits in several cognitive domains prior to surgery. Multiple methodological limitations were identified which include the lack of pre-treatment assessments, variations in the number and types of neuropsychological tests used, the normative data used to identify patients with cognitive deficits, and the variety of definitions for cognitive impairment. From 1012 initially identified articles, 11 met the inclusion criteria for this review. PubMed and Web of Science electronic databases were searched until December 2015.

This systematic review evaluates relevant findings and methodologic aspects of studies on cognitive functioning in meningioma patients prior to and/or following surgery with or without adjuvant radiotherapy.

Endnote x7 word 2016 repeated citations short title